FIG. 4.

Motor coordination assessed on an accelerating rotarod. Both mild and severe levels of CCI significantly impaired motor coordination on the 3 days immediately after traumatic brain injury (TBI; A and B, respectively). Mice with severe CCI continued to show impairments 1 week postinjury, but all mice had equivalent performance to sham controls by 14 days post-CCI. Injured mice and sham-treated mice are represented by broken lines and solid lines, respectively; pound sign (#) denotes a significant effect of the represented injury level on the given test day. CCI, controlled cortical impact.