Table 2.
Gene family | Proportion of genes with no DE | Family size | No. conditions with at least 1 DE gene | Average no. of conditions in which a gene is DE within gene family |
---|---|---|---|---|
HMG-Box | 0.06 | 17 | 25 | 5.06 |
GTPase | 0 | 8 | 20 | 5.13 |
Cyclin B & related kinase-activating proteins | 0 | 6 | 18 | 6.33 |
Putative N2.N2-dimethylguanosine tRNA methyltransferase | 0.50 | 2 | 8 | 5 |
TPR repeat-containing protein | 0 | 6 | 14 | 3.83 |
Failed axon connections (fax) proteins | 0 | 3 | 11 | 4.67 |
Tyrosine kinases | 0 | 5 | 8 | 3.6 |
RNA polymerase II transcription initiation factor TFIIH | 0 | 1 | 2 | 2 |
Chitinase | 0.04 | 67 | 46 | 5.60 |
Trypsin | 0.05 | 84 | 46 | 7.32 |
Collagens (type IV and type XIII). and related proteins | 0.08 | 108 | 40 | 5.14 |
Bestrophin | 0 | 24 | 25 | 4.46 |
FOG: 7 transmembrane receptor | 0.15 | 73 | 33 | 4.27 |
Low-density lipoprotein receptors | 0.03 | 30 | 33 | 7.57 |
Nucleolar GTPase/ATPase p130 | 0.09 | 54 | 32 | 3.74 |
Cytochrome P450 CYP4/CYP19/CYP26 subfamilies | 0 | 29 | 35 | 6.34 |
C-type Lectin | 0.14 | 74 | 43 | 5.46 |
Fibroblast/platelet-derived growth factor receptor | 0.08 | 24 | 31 | 4.21 |
RNA polymerase II. Large subunit | 0.04 | 65 | 32 | 4.55 |
A gene is considered as differentially expressed in the array (DE) if it has a q value smaller than 0.05. Gene families above the black line are overrepresented for differentially methylated genes, gene families below the black line are underrepresented for differentially methylated genes (see also table 1).