Table 1.

Summary of patients’ disease severity index according to the Mayo Clinic²⁰

	Pre-HBOT	Post-HBOT	p Value*
Stool frequency (median/range)	7 (3–20)	1 (0.5–3)	<0.001
Blood passage (number of patients)	10	0	0.002
Endoscopy
Grade 0	0	25	<0.001†
Grade I	2	7
Grade II	20	0
Grade III	10	0
Severity score index‡ (median/range)	7 (5–9)	0 (0–3)	<0.001

*p Value driven from the Wilcoxon singed ranks test. †p Value is calculated using the same test for the central tendency and dispersion of all grades, not only grade 0.

‡Scoring was calculated using 9 instead of 12 levels, due to the absence of detailed data about severity of passage of blood per anus, which was excluded from the nominator.

HBOT, hyperbaric oxygen therapy.