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. 2015 Nov 24;1:15038. doi: 10.1038/celldisc.2015.38

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Inactivation of Hppy enhanced Hpo target gene expression driven by Yki overexpression. (a–d) Eye discs of the indicated genotypes immunostained to show the expression of diap-GFP, an Hpo pathway responsive gene. Overexpression of UAS-Yki in the posterior region of eye discs by GMR-Gal4 (GMR>Yki) increased diap-GFP expression (b compared with a). Inactivation of Hppy or Hpo by RNAi enhanced diap-GFP expression driven by GMR>Yki (c and d compared with a and b).