Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov 3;1:15031. doi: 10.1038/celldisc.2015.31

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 SIBS, CAS

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Generation of ICAHCI offspring by H19^Δ1AG-haESCs. (a) Blastocysts generated by injection of H19^Δ1AG-haESCs into oocytes. The H19^Δ1AG-haESCs carried the Oct4-eGFP transgene. (b) Three SC pups from ICAHCI using H19^Δ1AG-haESCs. (c) Adult SC mice derived from ICAHCI using H19^Δ1AG-haESCs. (d) PCR analysis of H19 deletion in SC mice. (e) Adult H19^Δ1SC-Black mouse and its progeny. (f) PCR analysis of H19 deletion in the progeny of H19^Δ1SC-Black mice. The primer pairs P1–P2 and P3–P4 were used. (g) Adult H19^Δ1SC-Agouti mouse and its progeny. (h) PCR analysis of the H19 deletion in the progeny of SC-Agouti mice. (i) Methylation analysis of imprinting in H19^Δ1SC pups. C57BL/6 mice DNA was used as control. Open circles represent unmethylated CpG sites, whereas filled circles represent methylated CpG sites.