. 2016 Apr 28;7(7):854–861. doi: 10.7150/jca.14777

Table 3.

Unadjusted and adjusted analyses of causes of death stratified according to Charlson Comorbidity Index (CCI) subgroups.

CCI category	Death/total patient, n(%)	Median OS, months (95% CI)	Overall mortality		Cancer-specific mortality		Noncancer-specific mortality
CCI category	Death/total patient, n(%)	Median OS, months (95% CI)	HR (95% CI)	AHR (95% CI)	HR (95% CI)	AHR(95% CI)	HR (95% CI)	AHR(95% CI)
0	5,888/25,749 (22.9)	NR	1 (reference)	1	1	1	1	1
1	2,358/7,986 (29.5)	NR	1.38 (1.32-1.45)^c	1.05 ( 1.00-1.11)^a	1.29 (1.21-1.36)^c	0.99 (0.94-1.06)	1.62 (1.49-1.76)^c	1.20 (1.10-1.31)^c
2	918/2,402 (38.2)	NR	1.94 (1.81-2.08)^c	1.12 (1.03-1.21)^b	1.64 (1.50-1.79)^c	0.97 (0.87-1.08)	2.64 (2.36-2.96)^c	1.44 (1.26-1.64)^c
3	297/687 (43.2)	65.4 (49.1-81.7)	2.46 (2.19-2.77)^c	1.21 (1.07-1.37)^c	2.16 (1.87-2.51)^c	1.32 (1.12-1.54)^b	3.18 (2.63-3.85)^c	1.76 (1.43-2.16)^c
4	150/299 (50.2)	46.7 (36.8-56.6)	3.08 (2.62-3.63)^c	1.43 (1.20-1.69)^c	2.36 (1.90-2.94)^c	1.47 (1.18-1.81)^c	4.85 (3.81-6.18)^c	2.36 (1.83-3.05)^c
5-8	93/165 (56.4)	25.0 (8.6-41.4)	4.12 (3.36-5.06)^c	2.22 (1.79-2.74)^c	3.37 (2.56-4.41)^c	1.82 (1.38-2.4)^c	5.93 (4.32-8.14)^c	3.11 (2.24-4.31)^c

OS: overall survival; CI: Confidence interval; NR: Not reached; HR: hazard ratio; AHR: adjusted hazard ratio. ^ap<0.05,^bp<0.01,^c p<0.001.