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. 2016 Apr 28;7(7):862–871. doi: 10.7150/jca.14440

Figure 5.

Figure 5

HMGA2 is a direct target of ANG. A, ChIP results showed that ANG was recruited to the promoter of HMGA2 during transcription activity (n = 3 experiments for all tests). B, Construction of plasmid psiCHECK-2-HMGA2-WT and plasmid psiCHECK-2-HMGA2-MU. C, Overexpression of ANG significantly enhanced the relative luciferase activity in psiCHECK-2-HMGA2-WT group. However, the relative luciferase activity difference in psiCHECK-2-HMGA2-MU group did not show statistical significance by overexpression of ANG (n = 3 experiments for all tests). * P < 0.05 versus control. ▲ P > 0.05 versus control. All experiments were carried out in triplicate.