Table 3.
Associations between BNP, echocardiographic variables and exercise capacity
| Controls r (p) | Aortic stenosis r (p) |
Mitral stenosis r (p) |
Aortic regurgitation r (p) |
Mitral regurgitation r (p) |
All valves r (p) | |
|---|---|---|---|---|---|---|
| LV end-diastolic volume index (mL/m2) | 0.22 (0.20) | 0.02 (0.93) | −0.24 (0.20) | 0.16 (0.34) | −0.02 (0.28) | −0.01 (0.85) |
| LV end-systolic volume index (mL/m2) | 0.13 (0.43) | 0.10 (0.59) | −0.06 (0.74) | 0.19 (0.24) | −0.19 (0.31) | 0.01 (0.86) |
| Left atrial area index (cm2/m2) | 0.10 (0.57) | 0.52 (0.002) | 0.86 (<0.0001) | 0.53 (0.001) | 0.42 (0.02) | 0.57 (<0.0001) |
| Pulmonary artery pressure (mm Hg) | 0.29 (0.08) | 0.40 (0.037) | 0.47 (0.008) | 0.39 (0.02) | 0.53 (0.002) | 0.36 (<0.0001) |
| Valve area/EROA index (cm2/m2) | – | −0.28 (0.10) | −0.23 (0.21) | 0.22 (0.18) | −0.05 (0.79) | - |
| Exercise capacity (METS) | 0.23 (0.16) | −0.44 (0.009) | −0.56 (0.001) | −0.11 (0.52) | −0.53 (0.001) | −0.38 (<0.0001) |
Pearson's correlation used for analysis.
BNP, brain natriuretic peptide; EROA, effective regurgitant orifice area; LVEDVI, left ventricular end-diastolic volume index; LVESVI, left ventricular end-systolic volume index; METS, metabolic equivalents.