Figure 7.

CgYap1, CgYap5, and CgYap7 define a transcriptional network at the cross-roads between iron homeostasis, oxygen consumption, and stress response. The plain arrows are regulations which were demonstrated to occur in C. glabrata. The dashed arrows are regulations which were demonstrated in S. cerevisiae and were just hypothesized by functional annotation transfer in C. glabrata. Targeted transcription factors are in blue, kinases and phosphatases in green, iron sulfur cluster binding proteins in red, and heme biosynthetic genes in pink.