Figure 2.

Mean change from baseline in GLOESS at week 12 in patients who did, or did not, also achieve DAS28 ≥1.2 improvement, in (A) patients who achieved DAS28 ≤3.2 at week 24 or (B) patients who achieved DAS28 ≥1.2 improvement at week 24. Patients who discontinued due to lack of efficacy, adverse event or withdrawal of consent are considered as non-responders. Error bars represent SEM. DAS28, Disease Activity Score 28; GLOESS, Global OMERACT-EULAR Synovitis Score; MCPs, metacarpophalangeal joints. GLOESS was calculated for each joint set using both hands, giving a potential score of 0–24 for MCPs 2–5, 0–132 for the 22 paired joint set, and 0–54 for the reduced (9 paired) joint set.