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. 2016 Apr 26;2(1):e000232. doi: 10.1136/rmdopen-2015-000232

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

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Improvement in PROs, TJC, SJC and PGA at month 6 in patients achieving (A) ACR70, (B) CDAI REM and (C) SDAI REM. For tofacitinib 5 and 10 mg BID treatment groups, low levels of improvement in PROs, TJC, SJC and PGA are reported in patients who were not responsive to the first clinical outcome. ACR, American College of Rheumatology; BID, twice daily; CDAI, Clinical Disease Activity Index; HAQ-DI, Health Assessment Questionnaire-Disability Index; MTX, methotrexate; PGA, physician's global assessment; PROs, patient-reported outcomes; PtGA, patient global assessment; REM, remission; SDAI, Simplified Disease Activity Index; SJC, swollen joint count; TJC, tender joint count.