Table 2.
Unadjusted estimates for the predictors of the difference between the percentage of doses taken on weekdays and weekends using Generalized Estimating Equations.
| Estimate | 95% CI | p value | |||
|---|---|---|---|---|---|
| Sex | Male vs. female | 1.42 | 0.04 | 2.80 | 0.04 |
| Age | Per 10 year increase | −0.58 | −1.30 | 0.15 | 0.12 |
| Treatment arm | mDOT vs. standard of care | 0.98 | −0.41 | 2.37 | 0.17 |
| Site | Haiti vs. other | −1.14 | −2.47 | 0.20 | 0.10 |
| Years on cART before entry | Per one year increase | −0.26 | −0.54 | 0.01 | 0.06 |
| CD4 count (cells/mm3) | Per 100 cell increase | 0.36 | −0.10 | 0.83 | 0.13 |
| Viral load (log 10 copies/ml) | Per 1 log increase | −0.35 | −1.18 | 0.48 | 0.41 |
| Binge drinking | Yes vs. No | 4.23 | 1.95 | 6.51 | <0.01 |
| *Any substance use last 30 days | Yes vs. No | −2.22 | −5.20 | 0.75 | 0.14 |
| Self-perception of health | Fair/poor vs. Excellent /Very good/Good | −2.09 | −3.29 | −0.89 | <0.01 |
| Quarter on the study | Per quarter increase | 0.44 | 0.13 | 0.76 | 0.01 |
Positive numbers represent an increase in the difference between weekday and weekend adherence.
*
Other than alcohol;
cART=combination antiretroviral therapy; mDOT=modified directly observed therapy; (Q1–Q3)=Interquartile range; s.d.=standard deviation; vs.=versus; Quarter on study= 4 successive 12-week period