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. Author manuscript; available in PMC: 2016 May 9.
Published in final edited form as: Vaccine. 2011 Sep 3;29(46):8302–8308. doi: 10.1016/j.vaccine.2011.08.093

Table 1.

Description of Brighton Criteria Definitions for GBS levels of diagnostic certainty

Brighton Level 1

  • Bilateral and flaccid weakness of limbs AND

  • Decreased or absent deep tendon reflexes in weak limbs AND

  • Monophasic illness pattern and interval between onset and nadir of weakness between 12h and 28 days and subsequent clinical plateau AND

  • Electrophysiologic findings consistent with GBS AND

  • Cytoalbuminologic dissociation (i.e., elevation of CSF protein level above laboratory normal value AND CSF total WBC < 50 cells/ul AND

  • Absence of an identified alternative diagnosis for weakness
Brighton Level 2

  • Bilateral and flaccid weakness of limbs AND

  • Decreased or absent deep tendon reflexes in weak limbs AND

  • Monophasic illness pattern and interval between onset and nadir of weakness between 12h and 28 days and subsequent clinical plateau AND

  • Electrophysiologic findings consistent with GBS OR

  • CSF total WBC < 50 cells/ul (with or without protein elevation) AND

  • Absence of an identified alternative diagnosis for weakness
Brighton Level 3

  • Bilateral and flaccid weakness of limbs AND

  • Decreased or absent deep tendon reflexes in weak limbs AND

  • Monophasic illness pattern and interval between onset and nadir of weakness between 12h and 28 days and subsequent clinical plateau AND

  • Absence of an identified alternative diagnosis for weakness