Table 1.
Serum indicator | Normal range | No treatment | Vehicle | 5 mg/kg | 15 mg/kg |
---|---|---|---|---|---|
BUN (mg/dL) | 15-40 | 22 ± 1.2 | 23 ± 1.2 | 21 ± 3.1 | 17 ± 2.6 |
Albumin (g/dL) | 2.5-4.0 | 3.4 ± 0.21 | 3.5 ± 0.12 | 3.4 ± 0.44 | 3.3 ± 0.15 |
Globulin (g/dL) | 1.3-3.0 | 2.3 ± 0.058 | 2.3 ± 0.12 | 2.4 ± 0.31 | 2.2 ± 0.15 |
Bilirubin (mg/dL) | 0.1-1.0 | 0.23 ± 0.058 | 0.2 ± 0 | 0.2 ± 0.1 | 0.2 ± 0 |
AST (U/L) | 30-300 | 140 ± 76 | 180 ± 93 | 130 ± 82 | 140 ± 52 |
ALT (U/L) | 30-200 | 83 ± 82 | 95 ± 48 | 100 ± 57 | 96 ± 46 |