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. 2016 Jan 5;2:15039. doi: 10.1038/celldisc.2015.39

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Copyright © 2016 SIBS, CAS

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HNit1 expression is reduced in dedifferentiated human colon cancer. Tissue microarrays with 219 human colorectal carcinoma samples were stained for hNit1 using the monoclonal anti-nitrilase1 (1C3) antibody. (a) Frequencies of negative (0), weakly positive (1), moderately positive (2) and strongly positive (3) stainings in tumour samples according to tumour staging. (b) Immunohistochemical staining of hNit1 in a well- (left) and a poorly differentiated (right) colorectal carcinoma (×100 magnification).