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. 2015 Jul 10;14:131. doi: 10.1186/s12943-015-0406-1

Table 1.

Correlation of Cox-2 & Fox-M1 co-expression with clinico-pathological parameters in colorectal carcinomaa

Total Both high Any-1-low p value
Number Percent Number Percent Number Percent
Total number of cases 697 232 33.3 465 66.7
Age
≤50 years 229 32.9 90 39.3 139 60.7 0.0191
>50 years 468 67.1 142 30.3 326 69.7
Sex
Male 358 51.4 116 32.4 242 67.6 0.6111
Female 339 48.6 116 34.2 223 65.8
Tumour Site
Left colon 548 82.3 176 32.1 372 67.9 0.5821
Right colon 118 17.7 41 34.8 77 65.2
Histological Type
Adenocarcinoma 628 90.1 200 31.9 428 68.1 0.0174
Mucinous Carcinoma 69 9.9 32 46.4 37 53.6
Tumour Stage
I 80 12.2 25 31.3 55 68.7 0.4160
II 233 35.4 75 32.2 158 67.8
III 266 40.4 98 36.8 168 63.2
IV 79 12.0 22 27.8 57 72.2
Differentiation
Well 66 9.5 21 31.8 45 68.2 0.3709
Moderate 549 78.8 178 32.4 371 67.6
Poor 82 11.8 33 40.2 49 59.8
Ki-67
High 590 87.7 209 35.4 381 64.6 0.0004
Low 83 12.3 14 16.9 69 83.1
p-AKT
High 454 72.3 169 37.2 285 62.8 0.0214
Low 174 27.7 48 27.6 126 72.4
MMP-9
High 342 52.2 129 37.7 213 62.3 0.0116
Low 313 47.8 89 28.4 224 71.6
Survival
OS 5 Years 73.6 68.5 0.4796

aData were not available for (Tumor Site NA = 31), (Tumor Stage NA = 39), (Ki-67 NA = 24), (p-AKT NA = 69) and (MMP-9 NA = 42)