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. Author manuscript; available in PMC: 2016 May 9.
Published in final edited form as: J Immunol. 2007 Nov 15;179(10):6770–6782. doi: 10.4049/jimmunol.179.10.6770

FIGURE 7. Increased number of apoptotic particles in the phagosomal compartment in macrophages that ingested SM4s-painted apoptotic C26.

FIGURE 7.

Murine peritoneal macrophages were grown on cover slips placed in 6-well plates and cocultured with apoptotic cells at 37°C for 1 h and subjected to ultrastructural analysis by electron microscopy. A, Quantification of apoptotic particles within phagosomes (arrows) between the two groups. Dense apoptotic material in the phagolysosomes (stars) of apoptotic cell-SM4s phagocytosing macrophages in comparison to the control. B and C, Number of apoptotic particle-containing phagosomes per macrophage and percent of macrophages that contain apoptotic material were evaluated. Results are presented as mean ± SEM from total of 80 macrophages from three experiments. Statistical differences were evaluated by Mann-Whitney U test. ***, p < 0.001.