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. Author manuscript; available in PMC: 2016 May 9.
Published in final edited form as: J Immunol. 2007 Nov 15;179(10):6770–6782. doi: 10.4049/jimmunol.179.10.6770

FIGURE 8. Increased uptake of SM4s-painted apoptotic cells is dominantly mediated by scavenger receptor SR-A.

FIGURE 8.

A, Before incubation with DiO-labeled apoptotic C26 cells, macrophages were incubated with a general scavenger receptor blocker (OxLDL), a SR-A blocker (AcLDL), control (nLDL), or vehicle at 37°C and subjected to flow cytometric analysis. B, Effect of maleylated BSA (MBSA) as a SR-blocker and BSA as a control on the uptake of apoptotic cells. C, Apoptotic (ApoC26) vs viable (ViaC26) cell uptake by macrophages. Data are presented as mean ± SEM of three experiments in duplicates. Statistical differences were evaluated by paired t test. *, p < 0.05 and **, p < 0.01.