Table 4.
Adjusted* β-coefficient ± standard errors (SE) for changes in periodontal disease measures corresponding to a 10 nmol/L difference in baseline 25(OH)D concentrations (nmol/L) stratified by baseline periodontal disease status† (n=655): the Buffalo OsteoPerio Study
| n | β-coefficient (SE) | P-value‡ | |
|---|---|---|---|
| ACH Side-by-side mean change (mm)δ | |||
| None | 175 | 0.003 (0.004) | 0.473 |
| Moderate | 332 | − 0.0009 (0.005) | 0.857 |
| Severe | 144 | − 0.012 (0.014) | 0.385 |
| P for interaction | 0.319 | ||
| CAL Whole-mouth mean change (mm) | |||
| None/Mild | 145 | − 0.014 (0.013) | 0.286 |
| Moderate | 404 | 0.010 (0.011) | 0.354 |
| Severe | 106 | − 0.037 (0.030) | 0.219 |
| P for interaction | 0.317 | ||
| PD Whole-mouth mean change (mm) | |||
| None/Mild | 145 | − 0.007 (0.010) | 0.531 |
| Moderate | 404 | 0.005 (0.007) | 0.517 |
| Severe | 106 | − 0.026 (0.024) | 0.291 |
| P for interaction | 0.586 | ||
| Change in the percent of gingival sites that bled upon assessment (%) | |||
| Tertile 1: Percent of gingival sites that bled at baseline (0–22.2) | 223 | −0.468 (0.431) | 0.279 |
| Tertile 2: Percent of gingival sites that bled at baseline (22.6–45.0) | 214 | 0.516 (0.509) | 0.312 |
| Tertile 3: Percent of gingival sites that bled at baseline (45.1–100) | 218 | 0.417 (0.617) | 0.500 |
| P for interaction | 0.542 |
Models are adjusted for age, education, frequency of dental visits, smoking status, diabetes status, current use of osteoporosis related medications or bone therapies, baseline periodontal disease measures, BMI and recreational physical activity.
Periodontal disease status is defined using the whole-mouth mean ACH and self-reported tooth loss due to periodontitis20 when analyzing the ACH side-by-side mean change measures. Periodontal disease status is defined using CDC/AAP defined categories23 when analyzing the CAL and PD whole-mouth mean change measures. Change in the percent of gingival sites that bled upon assessment is stratified by tertiles of percent of gingival sites that bled at baseline.
P-value for associated beta-coefficient.
Analyses include only 651 women because four women’s cement-enamel junctions were not visible on their baseline radiograph to determine baseline whole-mouth mean ACH.