Table 2. Proportions of participants with negative cultures at completion of intensive phase treatment.

Abbreviation: CI, confidence interval; MGIT, Mycobacterial Growth Indicator Tube.

Culture Medium for Endpoint Assessment	Investigational Arm PMHZ	Control Arm REHZ	Difference in % (95% CI)	P value
Modified intention-to-treat analysis population: missing week 8 result classified as culture positive
Löwenstein-Jensen solid culture	47/60 (78.3%)	43/51 (84.3%)	-6.0 (-19.9, 10.3)	0.47
MGIT liquid culture	37/47 (78.7%)	27/41 (65.9%)	12.9 (-7.8, 31.7)	0.23
Modified intention-to-treat analysis population: if week 8 result missing, then last result carried forward
Löwenstein-Jensen solid culture	53/60 (88.3%)	46/51 (90.2%)	-1.9 (-12.6, 10.7)	1.00
MGIT liquid culture	40/47 (85.1%)	29/41 (70.7%)	14.4 (-5.0, 30.5)	0.12
Per-protocol analysis population
Löwenstein-Jensen solid culture	46/49 (93.9%)	41/45 (91.1%)	2.8(-8.1, 12.0)	0.71
MGIT liquid culture	36/38 (94.7%)	26/36 (72.2%)	22.5(3.0, 31.4)	0.01