Skip to main content
. 2016 May 9;11(5):e0155107. doi: 10.1371/journal.pone.0155107

Fig 2. P2X7R and pannexin 1 channels contribute to OFSS-induced ATP release from MLO-Y4 cells.

Fig 2

Comparison of OFSS-induced ATP release from MLO-Y4 cells under control glucose condition (Ctrl: 100 mg/dL of glucose) and in the presence of P2X7R blockers (10 μM A438079, 10 μM A740003) or Panx1 blocker (100 nM MFQ) or combined A438079 + MFQ or A740003 + MFQ. ATP release under each condition was normalized by number of counted cells (****P<0.0001 control static vs. control OFSS; **P<0.001 static vs. OFSS for A438079 and A740003 treated conditions; ++++P<0.0001 control OFSS vs. A438079 or A740003 or MFQ or MFQ+A438079 or MFQ+A740003 treated OFSS, n = 7–8. Data are presented as the means ± SEM).