TABLE 4.

Percentage of effect (percentage of cytotoxicity) relative to untreated controls

Values include the following: cell number, percentage reduction; intracellular free calcium, percentage increase; nuclear size, percentage reduction; membrane permeability, percentage increase; mitochondrial membrane potential, percentage reduction. Data represent the mean of triplicate wells (n = 3).

Test	TIR-199 (100 nm)	BTZ (5 nm)
	%	%
Cell number	62	98
Intracellular free Ca2+	27	29
Nuclear size	84	92
Membrane permeability	93	99
Mitomembrane potential	98	100