TABLE 1.
Rates of proton extrusion from prostatic carcinoma cells
Cell type | Medium | ECAR | pH decreasea | JH+, obs |
---|---|---|---|---|
μV s−1 | units min−1 | nm min−1 (%) | ||
PC-3 | Na+-HBSS | 320 ± 40b (n = 10) | 0.32 ± 0.04 | 43.3 ± 5.4 (100) |
PC-3 | Choline-HBSS | 211 ± 78 (n = 13) | 0.21 ± 0.08 | 28.6 ± 10.6 (66) |
LNCaP | Na+-HBSS | 283 ± 61b (n = 9) | 0.28 ± 0.06 | 37.9 ± 8.3 (88) (100) c |
LNCaP | Choline-HBSS | 184 ± 52 (n = 6) | 0.18 ± 0.05 | 24.4 ± 7.0 (56) (64)c |
a Data are from an initial pH of 7.4 (40 nm H+).
b tobt = 1.56, p > 0.05, not different (two-tailed t-test).
c Relative rates are for LNCaP cells.