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. 2016 Jan 29;291(16):8653–8662. doi: 10.1074/jbc.M115.713149

FIGURE 5.

FIGURE 5.

The role of NOXO1 in LSS/OSS regulation of NO and superoxide production. siRNA was used to inhibit the NOX regulatory subunit NOXO1 to examine its role in the endothelial responses to LSS and OSS. A, expression of NOXO1 in response to LSS/OSS with and without siRNA treatment (n = 4). B, superoxide measured from control or NOXO1-siRNA treated cells under static, LSS, or OSS conditions (n = 3). C, NO measured from control or NOXO1 siRNA-treated cells under static, LSS, or OSS conditions (n = 3); *, p ≤ 0.05.