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. 2016 Feb 25;291(17):8987–8999. doi: 10.1074/jbc.M115.704825

TABLE 1.

HK, PFK, and PK activities in clinical tumor samples

Unit Enzyme activity
Tumor description Refs.
HK PFK PK
Units/mg of protein 0.076 ± 0.045 0.324 ± 0.158 1.94 ± 1.18 B-CLL 38
Units/mg of protein 0.006 ± 0.001 0.017 ± 0.002 0.773 ± 0.128 Malignant cervix uteri 39
Units/g of protein 30.3 ± 19.6 71.5 ± 45.5 1910 ± 2550 Uterus cervix carcinoma 40
28.1 ± 16.1 91.4 ± 61.4 1440 ± 1040 Uterus endometrium carcinoma
Units/mg of protein 0.052 ± 0.003 0.048 ± 0.003 0.977 ± 0.079 Breast carcinomas 41
0.032 ± 0.007 0.027 ± 0.008 0.455 ± 0.131 Intraductal carcinoma
0.064 ± 0.006 0.053 ± 0.005 1.118 ± 0.136 Carcinoma with combined histology
0.032 ± 0.007 0.033 ± 0.013 0.726 ± 0.256 Lobular carcinoma
Units/mg of protein 0.052 ± 0.003 0.048 ± 0.003 0.977 ± 0.079 Primary breast cancer 42
0.083 ± 0.007 0.065 ± 0.006 1.28 ± 0.182 Metastatic breast cancer
mol/h/kg dry weight 0.46 ± 0.20 0.23 ± 0.23 0.94 ± 0.53 Malignant mammary tumor 43
Units/mg of protein 0.032 ± 0.007 \ 1.54 ± 0.031 Lung tumor 44
Units/mg of protein 0.036 ± 0.023 \ 1.26 ± 0.084 Neuroblastoma 45
Units/g of wet weight 1.3 ± 0.2 \ 25.2 ± 4.2 Primary malignant hepatoma 46
Units/mg of protein 0.05–0.015 \ 2.88–0.84 Retinoblastoma 47
Units/100 mg of tissue 0.040 ± 0.005 \ 6.590 ± 0.630 Infiltrating ductal breast carcinoma 48
Units/mg of DNA 0.116 ± 0.01 \ 9.84 ± 0.64 Infiltrating ductal carcinoma 49
Units/mg of protein 0.025 ± 0.003 \ 0.95 ± 0.14 All human breast cancer tissues 50
0.028 ± 0.005 \ 1.23 ± 0.2 Primary breast cancer
0.019 ± 0.003 \ 0.66 ± 0.06 Metastatic breast cancer
0.015 ± 0.004 \ 0.38 ± 0.07 Chest wall
0.010 ± 0.006 \ 0.56 ± 0.06 Lung
0.032 ± 0.018 \ 1.45 ± 0.64 Lymphoma
0.0144 \ 1.24 Bone
0.021 ± 0.010 \ 0.25 ± 0.13 Brain
0.014 \ 1.24 Liver
0.021 ± 0.006 \ 0.70 ± 0.09 Lymph node