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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: J Mol Cell Cardiol. 2016 Mar 16;94:1–9. doi: 10.1016/j.yjmcc.2016.03.006

Figure 3. Cardiac acyl CoA increases with ACSL1 overexpression.

Figure 3

(A) Total acyl CoA content (12C and 13C) of chain lengths 14-24 carbons. Note elevated content in ACSL1 male (n = 6) and ACSL1 female hearts (n = 5) versus male NTG (n = 5) and female NTG hearts (n = 9). (B) Content of 13C-enriched acyl CoA species. Note greatly elevated content in male ACSL1 hearts. (C) Percent of total acyl CoA pool enriched with 13C species. Note increased 13C acyl CoA content despite consistent percent 13C enrichment of the acyl CoA with ACSL1 overexpression. (D) Distribution of acyl CoA species by chain length. Female NTG OVX n = 6 and female ACSL1 OVX n = 6. *p < 0.05, **p < 0.01, and ***p < 0.001.