Table 2.
Regions with increase degree centrality in patients with ALS compared with healthy controls in weighted networks.
| Areas | Voxel sizea | Voxels structure (BA)b | Peak MNI coordinateb | Peak intensity (T value) | Peak MNI coordinate region | ||
|---|---|---|---|---|---|---|---|
| X | Y | Z | |||||
| Area 1 | 190 | –27 | –69 | –48 | 4.3181 | Left Cerebellum Posterior Lobe7 | |
| Area 2 | 97 | –3 | –87 | –36 | 4.6095 | Left Cerebellum Crus 2 | |
| Area 3 | 38 | 33 | –69 | –42 | 3.4569 | Right Cerebellum Crus 2 | |
| Area 4 | 19 | –15 | –75 | –27 | 3.6728 | Left CerebellumCrus 1 | |
| Area 5 | 107 | BA18/19 | –33 | –87 | –18 | 4.044 | Left Lingual gyrus |
| Area 6 | 35 | BA11 | 24 | 42 | –21 | 3.4221 | Right Middle Orbital Frontal gyrus |
| Area 7 | 22 | BA18/19 | 36 | –96 | –9 | 3.6865 | Right inferior Occipital gyrus |
| Area 9 | 19 | BA18 | 9 | –94 | –12 | 3.087 | Right Lingual gyrus |
| Area 19 | 49 | BA8/9 | 12 | 45 | 54 | 3.8211 | Superior Frontal gyrus |
a
Statistical significance was set at a voxel-wise p < 0.01, in conjunction with cluster wise AlphaSim (rmm = 5, clusters = 18) to correct for multiple comparisons.
b
BA, Brodmann area; MNI, Montreal Neurological Institute.