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. 2016 May 10;10:45. doi: 10.3389/fncom.2016.00045

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Copyright © 2016 Li, Wang, Ke, Liu, Yuan, Zhang, Xiong and Qiu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Experimental design and subjective pain intensity perception. (A) The experiment consisted of four order-fixed 20-min conditions in two sessions. Session 1: (I) control, (II) pain; Session 2: (III) control with placebo, (IV) pain with placebo. Innocuous and noxious stimulations were respectively applied in control conditions (I and III) and pain conditions (II and IV). (B) The subjective pain intensity (mean ± SEM) was collected every 15 s for each condition from all placebo responders (N = 14).