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. 2016 May 10;6:25660. doi: 10.1038/srep25660

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(A) The average number of LFOs detected per day during the latent period in sham perforant pathway transection (PPT) (8 h PPS, no PPT), PPT, and Control (8 h PPS, no PPT, did not develop epilepsy) (n = 4 per group). LFO occurrence was essentially the same in both Sham PPT and PPT groups (p > 0.05). No LFOs were detected in the Control group. (B) Average LFO occurrence per hour on seizure-free days (orange) and during the 60 minutes immediately prior to a spontaneous seizure (green). LFO occurrence usually decreased markedly in the hour preceding a spontaneous seizure (p < 0.001).