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. 2016 May 10;6:25687. doi: 10.1038/srep25687

Figure 7.

Figure 7

Changes of TM-score (a) and the number of atom clashes (b) of the models for two CASP11 targets during the simulated annealing. TM-score stochastically went up and down with an overall upward trend during simulated annealing. Even though the final model was not the best one, but it was close to the best one and better than the initial model. Moreover, the number of clashes rather consistently decreased during simulated annealing.