FIG 2.

ABCs IPD rates in the population of individuals <5 years of age in 1999 (before PCV7 introduction), 2009 (9 years after PCV7 introduction), and 2013 (3 years after PCV13 introduction). The bright red portions indicate penicillin resistance (MICs of ≥2 μg/ml), lighter red indicates intermediate resistance (0.12 to 1.0 μg/ml), and gray indicates sensitivity (≤0.06 μg/ml). PCV13 types, besides those targeted by PCV7, are indicated in red and purple. Only nonvaccine types (NVT) that are found associated with intermediate or high penicillin resistance are specifically indicated in black boldface type.