Table 2.

The effects of MK-801 and PWZ-029 administration on the rat’s behavior in the MWM. Two-way repeated measures ANOVA and overall post hoc results for latency (s), total distance (m), mean speed (m/s) and path efficiency. MK = 0.1 mg/kg MK–801; PWZ 2 = 2 mg/kg PWZ–029; PWZ 5 = 5 mg/kg PWZ–029; PWZ 10 = 10 mg/kg PWZ–029; ns = not significant

Two–way repeated measures ANOVA
Factor	Latency	Total distance	Mean speed	Path efficiency
Treatment: F(4,34)	9.497	5.847	3.341	10.431
p	< 0.001	0.001	0.021	< 0.001
Days: F(4,136)	33.248	26.229	1.592	19.729
p	< 0.001	< 0.001	0.180	< 0.001
Interaction: F(12,136)	1.410	0.662	1.157	2.100
p	0.410	0.826	0.311	0.481
SNK post hoc for Treatment
MK + SOL vs. SAL + SOL	< 0.001	< 0.001	ns	< 0.001
MK + PWZ 2 vs. SAL + SOL	0.035	0.005	ns	0.002
MK + PWZ 5 vs. SAL + SOL	0.002	0.004	ns	< 0.001
MK + PWZ 10 vs. SAL + SOL	< 0.001	0.006	0.028	< 0.001
MK + PWZ 2 vs. MK + SOL	0.022	ns	ns	ns
MK + PWZ 5 vs. MK + SOL	ns	ns	ns	ns
MK + PWZ 10 vs. MK + SOL	ns	ns	ns	ns
MK + PWZ 2 vs. MK + PWZ 5	ns	ns	ns	ns
MK + PWZ 2 vs. MK + PWZ 10	0.042	ns	ns	ns

MK = 0.1 mg/kg MK–801; PWZ 2 = 2 mg/kg PWZ–029; PWZ 5 = 5 mg/kg PWZ–029; PWZ 10 = 10 mg/kg PWZ–029; ns = not significant