Table 5.
Short-Term (3 Months) Mortality in ACLF Cases as per Acute Predisposing Event.
| Acute predisposing agent | Total cases predisposed, N (%) | Followed up cases, N (%) | Cases died, N (%) |
|---|---|---|---|
| Single insult | 88 (71.54) | 62 (70.45) | 40 (66.12) |
| Alcohol intake | 30 (34.09) | 22 (73.33) | 21 (95.45) |
| HAV infection | 6 (6.81) | 6 (4.87) | 3 (50) |
| HBV flare | 7 (7.95) | 5 (71.42) | 3 (60) |
| Infection | 22 (25) | 16 (69.56) | 6 (37.5) |
| Hepatotoxic medication | 6 (6.81) | 3 (50) | 1 (33.33) |
| Variceal bleed | 2 (2.27) | 1 (50) | 0 (0) |
| Unknown predisposition | 15 (17.04) | 9 (60) | 7 (77.77) |
| Multiple insults (Probable sequential order of individual acute insults) | 35 (28.45) | 27 (77.14) | 22 (81.48) |
| Alcohol intake → Infection | 12 (34.28) | 10 (37.03) | 9 (90) |
| Alcohol intake → Indigenous drugs | 6 (17.14) | 4 (14.81) | 2 (50) |
| Infections → Indigenous drugs | 4 (11.42) | 2 (7.4) | 2 (100) |
| Infections → Variceal bleed | 3 (8.57) | 2 (7.4) | 1 (50) |
| Infection → Falciparum malaria | 3 (8.57) | 2 (7.4) | 1 (50) |
| Alcohol intake → Acute HAV infection | 2 (5.71) | 2 (7.4) | 2 (100) |
| Alcohol intake → Variceal bleed | 1 (2.85) | 1 (3.7) | 1 (100) |
| Alcohol intake → HBV Flare → Antitubercular drugs | 2 (5.71) | 2 (7.4) | 2 (100) |
| Acute HEV Infection → Indigenous drugs → Infection | 1 (2.85) | 1 (3.7) | 1 (100) |
| Acute HAV infection → Indigenous drugs → Infection | 1 (2.85) | 1 (3.7) | 1 (100) |
N: number; →: followed by; HAV: hepatitis A virus; HBV: hepatitis B virus; HEV: hepatitis B virus.