Table 2.
Predictors of Alcohol Relapse After Liver Transplantations in Different Studies.
| Author, year | N | Pretransplant factors | Demographic factors | Psychosocial factors | Post-transplant |
|---|---|---|---|---|---|
| Björnsson,23 2005 | 103 | Structured management program decreased relapse | a | a | Structured management program decreased relapse |
| DiMartini,24 2006 | 167 | Length of sobriety | a | Alcohol dependence, other substance use, and prior alcohol rehabilitation | a |
| Pfitzmann,25 2007 | 300 | Abstinence <6 months | Absence of companion in life, presence of young children, and poor psychosomatic prognosis | ||
| De Gottardi,26 2007 | 387 | Abstinence <6 months | a | High-risk alcoholism relapse high score (4–6), and presence of psychiatric comorbidity | a |
| Gedaly,27 2008 | Abstinence <12 months | a | a | ||
| Tandon,28 2009 | Shorter pretransplant abstinenceb | ||||
| Karim,29 2010 | 80 | Abstinence <6 months | Female sex, age < 50 year | Psychiatric comorbidity | |
| Hartl,30 2011 | 120 | Abstinence of <3 months | a | Nonacceptance of having an alcohol problem | a |
| Rodrigue,31 2013 | 118 | Absence of hepatocellular carcinoma Tobacco dependence Continued alcohol use after liver disease diagnosis |
a | Low motivation for alcohol treatment, Poor stress management skills, no rehabilitation relationship, limited social support, lack of nonmedical negative behavioral consequences, and continued engagement in social activities with alcohol | a |
| Deruytter,32 2013 | 108 | A shorter pretransplant abstinence (in univariate) | Presence of a first-degree relative with alcohol abuse | a | a |
| Egawa,33 2014 | 140 | Preoperative alcohol consumption was not a risk factor for relapse | a | History of treatment for psychiatric diseases other than alcoholism | a |
| Satapathy,11 2015 | 128 | Abstinence <6 months (in univariate) Active smoking |
Younger age No support of immediate family member |
Nonalcohol-related criminal history | a |
Not mentioned/not studied/not found important.
For every 1-month increment in pretransplant abstinence, authors found a 5% decrease in the adjusted relapse rate.