Table 1.

Summary of genomic studies on gastric cancer (GC)

Reference	Sample size	Ethnicity	Histology (Lauren’s type)				Technology platform							Molecular subtype
			Intestinal	Diffuse	Mixed	Not specified	WES	WGS	RNAseq	SNP/copy number microarray	Targeted sequencing	Gene expression microarray	DNA methylation profiling
[10]	49 (MSS only)	Korean	18	31	0	0		√						NA
[14]	294	Northern Chinese	139	155	0	0	√	√			√			High clonality and low clonality
[16]	75	Asian	196	69	19	11	√	√	√	√			√	EBV+, MSI, GS, and CIN
	220	Non-Asian
[17]	890	Asian	0	0	0	1016						√		NA
	126	Non-Asian
[18]	100	Chinese (Hong Kong)	57	29	14	0		√		√		√	√	NA
[22]	386	Singaporean	253	183	82	3						√		Genomic intestinal and genomic diffuse
	65	Korean
	70	Australian
[23]	19	Korean	5	14	0	0	√	√						NA
[24]	300	Korean	150	142	8	0				√	√	√		MSS/TP53−, MSS/TP53+, MSS/EMT, and MSI
[25]	103	Korean	61	36	5	1	√			√				NA
[26]	22	Chinese (Hong Kong)	18	2	2	0	√							NA
[27]	15	Singaporean	11	3	1	0	√			√		√		NA
[28]	87	Japanese	0	87	0	0	√				√			NA
[29]	36	Non-Asian	12	10	14	0						√		Proximal non-diffuse, diffuse, and distal non-diffuse
[30]	17	Non-Asian	0	0	0	51	√		√	√				NA
	34	Vietnamese
[31]	116	Non-Asian	12	24	0	80					√			NA

WES whole-exome sequencing, WGS whole-genome sequencing, RNAseq RNA sequencing, SNP single-nucleotide polymorphism, MSS microsatellite stable, NA not available, EBV, Epstein-Barr virus, MSI microsatellite instability, GS genomically stable, CIN chromosomal instability, TP53 tumor protein 53, EMT epithelial-to-mesenchymal transition