Table 1.
Reference | Sample size | Ethnicity | Histology (Lauren’s type) | Technology platform | Molecular subtype | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Intestinal | Diffuse | Mixed | Not specified | WES | WGS | RNAseq | SNP/copy number microarray | Targeted sequencing | Gene expression microarray | DNA methylation profiling | ||||
[10] | 49 (MSS only) | Korean | 18 | 31 | 0 | 0 | √ | NA | ||||||
[14] | 294 | Northern Chinese | 139 | 155 | 0 | 0 | √ | √ | √ | High clonality and low clonality | ||||
[16] | 75 | Asian | 196 | 69 | 19 | 11 | √ | √ | √ | √ | √ | EBV+, MSI, GS, and CIN | ||
220 | Non-Asian | |||||||||||||
[17] | 890 | Asian | 0 | 0 | 0 | 1016 | √ | NA | ||||||
126 | Non-Asian | |||||||||||||
[18] | 100 | Chinese (Hong Kong) | 57 | 29 | 14 | 0 | √ | √ | √ | √ | NA | |||
[22] | 386 | Singaporean | 253 | 183 | 82 | 3 | √ | Genomic intestinal and genomic diffuse | ||||||
65 | Korean | |||||||||||||
70 | Australian | |||||||||||||
[23] | 19 | Korean | 5 | 14 | 0 | 0 | √ | √ | NA | |||||
[24] | 300 | Korean | 150 | 142 | 8 | 0 | √ | √ | √ | MSS/TP53−, MSS/TP53+, MSS/EMT, and MSI | ||||
[25] | 103 | Korean | 61 | 36 | 5 | 1 | √ | √ | NA | |||||
[26] | 22 | Chinese (Hong Kong) | 18 | 2 | 2 | 0 | √ | NA | ||||||
[27] | 15 | Singaporean | 11 | 3 | 1 | 0 | √ | √ | √ | NA | ||||
[28] | 87 | Japanese | 0 | 87 | 0 | 0 | √ | √ | NA | |||||
[29] | 36 | Non-Asian | 12 | 10 | 14 | 0 | √ | Proximal non-diffuse, diffuse, and distal non-diffuse | ||||||
[30] | 17 | Non-Asian | 0 | 0 | 0 | 51 | √ | √ | √ | NA | ||||
34 | Vietnamese | |||||||||||||
[31] | 116 | Non-Asian | 12 | 24 | 0 | 80 | √ | NA |
WES whole-exome sequencing, WGS whole-genome sequencing, RNAseq RNA sequencing, SNP single-nucleotide polymorphism, MSS microsatellite stable, NA not available, EBV, Epstein-Barr virus, MSI microsatellite instability, GS genomically stable, CIN chromosomal instability, TP53 tumor protein 53, EMT epithelial-to-mesenchymal transition