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. 2016 May 10;17:347. doi: 10.1186/s12864-016-2682-6

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© Nettling et al. 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Mean information content and standard error for motifs of five transcription factors in five species. The information content of motifs in the reference species (human) is significantly higher compared to the four phylogenetically related species (p<1.8×10⁻¹⁴). The information content typically decreases with the phylogenetic distance from the reference species