Table 2.

Multivariable logistic regression with baseline serum uric acid (UA) as a predictor of the metabolic syndrome (MetS) and its components after seven years, unstratified. The odds ratio (OR) is per 59 μmol/L increase of UA. The group includes the subjects without MetS at baseline

	Number	Cases	OR	95 % CI	P value
Risk of elevated blood pressure	3701	2847	1.15	[1.04–1.27]	0.006
Risk of elevated triglycerides	3693	941	1.32	[1.22–1.42]	<0.001
Risk of low HDL	3690	553	1.27	[1.16–1.39]	<0.001
Risk of elevated fasting glucose	3689	333	1.13	[1.02–1.26]	0.021
Risk of central obesity	3677	1031	1.07	[0.97–1.18]	0.130
Risk of MetS	3660	611	1.29	[1.18–1.41]	<0.001

Covariates: sex, age, systolic blood pressure, total cholesterol, current smoking, physical activity, HbA1c, eGFR, use of diuretics, alcohol consumption, and waist circumference

Elevated blood pressure = blood pressure ≥ 130/85 mm Hg or treated for hypertension, elevated triglycerides = triglycerides ≥ 2.28 mmol/L if time since last meal <4 h and ≥1.7 mmol/L if time since last meal ≥4 h or use of lipid lowering drugs, low HDL = HDL < 1.03 mmol/L in men or <1.30 mmol/L in women, elevated fasting glucose = glucose ≥ 7.8 mmol/L if time since last meal <4 h and ≥5.6 mmol/L if time since last meal ≥4 h or treated for elevated glucose, central obesity = waist circumference ≥ 102 cm in men or ≥88 cm in women, MetS = three or more MetS components

Abbreviations: UA uric acid, OR odds ratio, BMI body mass index, CI confidence interval, HDL high-density lipoprotein, HBA1c hemoglobin A1c, eGFR estimated glomerular filtration rate, MetS metabolic syndrome