Table 4.

GO term analysis of differentially expressing genes between 3.0Pa-loaded and 0.05Pa + turbulent flow-loaded group

Over-presented term in 0.05Pa + turbulent flow-loaded group
Accession	Term	P-value	FDR
GO:0000786	nucleosome	7.7E-54	3.0E-51
GO:0006334	nucleosome assembly	6.4E-53	1.3E-50
GO:0000278	mitotic cell cycle	3.8E-26	5.1E-24
GO:0007067	mitosis	9.7E-26	9.6E-24
GO:0046982	protein heterodimerization activity	9.7E-24	7.7E-22
GO:0005654	nucleoplasm	5.6E-19	3.7E-17
GO:0060968	regulation of gene silencing	8.7E-15	4.7E-13
GO:0003677	DNA binding	9.5E-15	4.7E-13
GO:0005819	spindle	8.5E-14	3.7E-12
GO:0000775	chromosome, centromeric region	3.5E-13	1.4E-11
GO:0005634	nucleus	4.8E-13	1.7E-11
GO:0000777	condensed chromosome kinetochore	9.2E-13	3.1E-11
GO:0034080	CENP-A containing nucleosome assembly at centromere	5.9E-12	1.8E-10
GO:0007059	chromosome segregation	1.6E-11	4.5E-10
GO:0006260	DNA replication	1.1E-10	2.9E-09
GO:0030496	midbody	1.6E-10	3.9E-09
GO:0031536	positive regulation of exit from mitosis	2.1E-10	4.8E-09
GO:0000922	spindle pole	3.6E-10	7.8E-09
GO:0005876	spindle microtubule	1.9E-09	4.0E-08
GO:0006281	DNA repair	2.5E-09	5.0E-08
Under-presented term in 0.05Pa + turbulent flow-loaded group
Accession	Term	P-value	FDR
GO:0002113	interleukin-33 binding	2.9E-07	5.9E-05
GO:0002114	interleukin-33 receptor activity	2.9E-07	5.9E-05
GO:0043032	positive regulation of macrophage activation	7.9E-07	1.1E-04
GO:0090197	positive regulation of chemokine secretion	1.0E-06	1.1E-04
GO:0004908	interleukin-1 receptor activity	1.5E-06	1.2E-04
GO:0002826	negative regulation of T-helper 1 type immune response	1.7E-06	1.2E-04
GO:0032754	positive regulation of interleukin-5 production	3.6E-05	2.1E-03
GO:0070698	type I activin receptor binding	5.9E-05	3.0E-03
GO:0071310	cellular response to organic substance	1.1E-04	4.9E-03
GO:0030617	inhibitory cytoplasmic mediator activity	1.2E-04	4.9E-03

FDR false discovery rate