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. 2016 May 3;9:2601–2613. doi: 10.2147/OTT.S101209

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© 2016 Lin et al. This work is published and licensed by Dove Medical Press Limited

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Schematic diagram showing the proposed mechanism of action of pSur/AS-Sur in survivin-expressing cancer cells.

Abbreviations: mRNA, messenger RNA; AIF, apoptosis-inducing factor; pSur/AS-Sur, survivin promoter-driven antisense survivin.