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. 2016 Jan 19;9(3):121–125. doi: 10.1080/19336934.2015.1131882

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Figure 2. — Mutations in peo cause telomeric fusion that preferentially involve Ha-telomeres. (A) Examples of telomeric fusions in peo mutant neuroblasts. (A1-2) Control (Oregon-R) male (A1) and female (A2) metaphases; (A3-A6) metaphases from peo mutant brains showing: (A3) a ring Y chromosome (arrowhead) and a 4 (arrow)-4-XR tricentric chromosome; (A4) two 4-XR telomeric fusions (arrows); (A5) a 4 (arrow)-YS · YL. -XR tricentric chromosome; (A6) an XR-XR telomeric fusion (arrow). (B) Frequencies of telomeric fusions involving Ha-telomeres in different telomere fusion mutants. The red and pink columns represent the frequencies of Ha- (red) and non-HA (autosomal and XL pink) telomeres calculated assuming a random involvement of telomeres in fusion events. The peo^h and peo¹ are weak and strong peo mutant alleles, respectively.