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Macroscopic lung pathology of mouse. The biofilms of alginate beads of NH57388A were administered by the intratracheal route to the lower left lung either left untreated (A) or with 5% OligoG (50 mg/ml) treatment only (B), with local 5% OligoG treatment and 16×MIC aztreonam treatment (C), with local 5% OligoG and 16×MIC colistin treatment (D), and with local 5% OligoG and 16×MIC tobramycin treatment (E). Lungs were removed at 24 h after bacterial challenge.
