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MBEC in vitro of OligoG CF-5/20 with ciprofloxacin and colistin on P. aeruginosa PAO1 alginate bead biofilm in saline
| Treatment time (h) | MBECa (μg/ml) |
|||
|---|---|---|---|---|
| Ciprofloxacin |
Colistin |
|||
| 0% OligoG | 5% OligoG | 0% OligoG | 5% OligoG | |
| 1 | 8 | 4 | >256 | 256 |
| 2 | 8 | 4 | >256 | 128 |
| 4 | 8 | 4 | 64 | 16 |
| 8 | 4 | 1 | 16 | 4 |
| 12 | 2 | 0.5 | 8 | 4 |
| 24 | 1 | 0.5 | 4 | 4 |
Etest for P. aeruginosa PAO1 found a colistin MIC of 2 μg/ml and a ciprofloxacin MIC of 0.125 μg/ml.
