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. 2016 Apr 22;60(5):3041–3050. doi: 10.1128/AAC.02928-15

TABLE 4.

Correlations between the fecal acetic acid levels and tight-junction-related gene expression in the intestinal epithelium on day 14 after MDRAb infection

Site and gene producta Correlation between fecal acetic acid levels and tight-junction-related gene expression (n = 24)
Pearson correlation coefficient P
Ileum
    Claudin-1 0.470 <0.05
    Occludin 0.695 <0.001
    ZO-1 0.559 <0.01
Cecum
    Claudin-1 0.503 <0.05
    Occludin 0.597 <0.01
    ZO-1 0.730 <0.001
Colorectum
    Claudin-1 0.659 <0.001
    Occludin 0.761 <0.001
    ZO-1 0.856 <0.001
a

Mice were infected with MDRAb, treated with BbY plus GOS, and treated with 5-FU, as described in the legend to Fig. 4. Feces were collected immediately before dissection of the mice (6 mice/group) on day 14 after infection with MDRAb, and the organic acid concentration was measured.