TABLE 1.

Inconsistencies between 18 mutation profiles of the TEM mutation table and the LacED

TEM variant	Mutation profile in TEM mutation table	GenBank accession no.	Mutation profile in LacED (derived from GenBank entry)a
TEM-42	Q39K, A42V, G238S, E240K, T265M	X98047	N-3, Q39K, A42V, G238S, E240K, T265M, C-2
TEM-59	Q39K, S130G	AF062386	Q39K, S130G, C-9
TEM-60	Q39K, L51P, E104K, R164S	AF047171	Q39K, L51P, E104K, R164S, A187R, S223C, F230L
TEM-75	L21F, R164H, T265M	AY130284	N-12, L21F, R164H, T265M, C-13
TEM-89	Q39K, E104K, S130G, G238S	AY039040	Q39K, E104K, S130G, G238S, C-8
TEM-98	Empty	AF397068	S4D, I5P, H289L
TEM-108	V80E, G196S, N276S	AF506748	S4D, I5P, V80E, G196S, N276S
TEM-117	L21F	AY130282	N-12, L21F, C-19
TEM-118	R164H, T265M	AY130285	N-12, R164H, T265 M, C-13
TEM-123	Q6K, E104K, G238S	AY327539	Q6K, E104K, G238S, A248-, R275A
TEM-124	Q6K, E104K, M182T	AY327540	Q6K, E104K, M182T, A248-, R275A
TEM-148	T189K	AM087454	T188K
TEM-187	L21F, R164H, A184V, T265M	HM246246	L21F, R164H, A184V, T265M, C-1
TEM-191	E240K	JF949916	N-10, E240K, C-24
TEM-192	M68I	JF949915	N-10, M68I, C-25
TEM-193	N136H, L138F, R164C, E166G, E168K, I173T, N175H, M186V, T188N, L220I	JN935135	N136H, L138F, R164C, E166G, E168K, N170T, N175H, M186V, T188N, L220I
TEM-199	Q39K, E104K, M155I, G238S	JX050178	N-3, Q39K, E104K, M155I, G238S
TEM-209	G41A	KF240808	G41D

^aA248-, deletion at position 248. The following abbreviations for differences were used: N-3, missing 3 amino acids at the N terminus; C-2, missing 2 amino acids at the C terminus; Q39K, mutation Q-K at position 39.