TABLE 1.
Antibiotic used, by temp | MIC (μg/ml) |
|||
---|---|---|---|---|
WT cells | ΔtolC cells | ΔmukB cells | ΔtolC ΔmukB cells | |
37°C | ||||
Novobiocin | 160 | 1 | 1.25 | 0.048 |
Erythromycin | 100 | 2 | 50 | 1 |
Norfloxacin | 0.08 | 0.04 | 0.04 | 0.01 |
Nalidixic acid | 6.4 | 0.8 | 1.6 | 0.25 |
Rifampin | 10 | 6.4 | 2.0 | 2.5 |
23°C | ||||
Novobiocin | 813 | 4 | 32 | 0.31 |
Erythromycin | 10 | 2 | 13 | 1 |
Norfloxacin | 0.032 | 0.02 | 0.04 | 0.01 |
Nalidixic acid | 6.4 | 0.4 | 6.4 | 0.25 |
Rifampin | 3.2 | 3.2 | 1.6 | 1.6 |