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. 2016 Apr 22;60(5):2949–2953. doi: 10.1128/AAC.03102-15

TABLE 1.

MIC (μg/ml) of the indicated antibiotics for MukB- and TolC-deficient cells

Antibiotic used, by temp MIC (μg/ml)
WT cells ΔtolC cells ΔmukB cells ΔtolC ΔmukB cells
37°C
    Novobiocin 160 1 1.25 0.048
    Erythromycin 100 2 50 1
    Norfloxacin 0.08 0.04 0.04 0.01
    Nalidixic acid 6.4 0.8 1.6 0.25
    Rifampin 10 6.4 2.0 2.5
23°C
    Novobiocin 813 4 32 0.31
    Erythromycin 10 2 13 1
    Norfloxacin 0.032 0.02 0.04 0.01
    Nalidixic acid 6.4 0.4 6.4 0.25
    Rifampin 3.2 3.2 1.6 1.6