TABLE 1.
Organism | β-Lactamase | MIC (μg/ml) |
||
---|---|---|---|---|
OP0595 | Cefepime | Cefepime-OP0595a | ||
E. coli MSC20613 | CTX-M-15 | 2 | >64 | ≤0.004 |
E. coli MSC20627 | CTX-M-15 | 2 | >64 | ≤0.004 |
E. coli MSC20653 | CTX-M-15, OXA-1 | 2 | >64 | ≤0.004 |
E. coli MSC20662 | CTX-M-15 | 2 | >64 | ≤0.004 |
E. coli MSC20670 | CTX-M-15, OXA-1 | 1 | >64 | ≤0.004 |
K. pneumoniae ATCC BAA-1705 | KPC-2 | 2 | >64 | ≤0.004 |
K. pneumoniae ATCC BAA-1898 | KPC-2 | 2 | 64 | ≤0.004 |
K. pneumoniae ATCC BAA-1899 | KPC-2 | 16 | >64 | ≤0.004 |
K. pneumoniae ATCC BAA-1900 | KPC-3 | 2 | 64 | ≤0.004 |
K. pneumoniae ATCC BAA-1904 | KPC-3 | 4 | >64 | ≤0.004 |
The combined concentration of OP0595 was fixed at 4 μg/ml.