Table 1.
Demographic and clinical characteristics of sequenced and genotyped subjects
| ET cases (N = 259) | Controls (N = 262) | Statistical test | P-value | |
|---|---|---|---|---|
| ET diagnosis: definite/probable/possible | 75/120/64 | 0 | Not applicable | Not applicable |
| % male (N) | 52.5 (136) | 43.1 (113) | χ2 = 4.6 | 0.03 |
| Mean age at tremor onset (years) (SD) | 43.0 (23.1) | Not applicable | Not applicable | Not applicable |
| Mean years of education (SD) | 15.3 (3.8) | 15.6 (3.3) | Unpaired t-test | 0.34 |
| % with family history of ET (N)** | 35.1 (91) | 1.1 (3) | χ2 = 101.9 | <0.0001 |
| % Ashkenazi Jewish ancestry (N)* | 36.7 (95) | 22.9 (60) | χ2 = 11.8 | 0.008 |
ET, essential tremor.
P < 0.0001;
P < 0.05.