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ROS production was not inhibited by corticosteroid PLP. Of the NPs, only PN and PSS did not inhibit ROS production. All other tested compounds showed an inhibition of ROS production with Emax values close to 100%.
| Compound | IC50 (μM) | Emax (%) | Fit (R2) |
|---|---|---|---|
| PLP | - | < 30 | - |
| EGCG | 5.9 | 92 | 0.91 |
| BBCl | 26.5 | 94 | 0.99 |
| Cur | 7.0 | 100 | 0.96 |
| Apo | 11.4 | 95 | 0.99 |
| Apo-e | 14.3 | 86 | 0.94 |
| PN | - | < 30 | - |
| PTS | 22.2 | 100 | 0.83 |
| PSS | > 1000 | 100 | 0.53 |
