FIG 10.
Cellular infiltrates and detection of R. typhi in the brains of C57BL/6 wild-type mice in the initial phase of infection. (A) C57BL/6 wild-type mice were infected with 2 × 106 SFU R. typhi i.v. Brain sections were prepared on day 8 postinfection and stained for IBA1 and CD3, as indicated. (B and C) The numbered boxed areas in panel A were further analyzed by staining of serial sections for IBA1, CD3, iNOS, and R. typhi, employing anti-R. typhi antibody (clone BNI52). (B) Area 1; (C) area 2.