FIG 6.
In vivo competitive infection with C3H/HeOuJ mice. UTI89 showed a significant competitive advantage over UTI89 ΔybtPQ::Kanr during in vivo competitive infections in C3H/HeOuJ mice. UTI89 and UTI89 ΔybtPQ::Kanr were mixed 1:1 to total of 107 CFU prior to coinfection. (A) Competitive indices were calculated from the bacterial titers collected from the bladders. (B) Competitive index values against total bacterial titers from the bladders are presented. Each symbol represents a datum from an individual mouse. Statistical significance was assessed using the Wilcoxon signed-rank test, with a log10 CI of 0 (dotted line) being the theoretical median. Numbers at the top indicate median values. *, P < 0.05. The bars indicate mean values.